Affecting approximately 23 million people worldwide, heart failure is amongst the most debilitating cardiovascular problems.
The research at a glance
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The research at a glance
2:16
The research at a glance
2:16
The research at a glance
2:16
01
Our objectives
01
Develop a Biocompatible Artificial Heart:
Develop a Biocompatible Artificial Heart: Create a soft, biocompatible artificial heart using advanced tissue engineering and soft robotics to improve the treatment of heart failure patients.
01
Develop a Biocompatible Artificial Heart:
Develop a Biocompatible Artificial Heart: Create a soft, biocompatible artificial heart using advanced tissue engineering and soft robotics to improve the treatment of heart failure patients.
01
Develop a Biocompatible Artificial Heart:
Develop a Biocompatible Artificial Heart: Create a soft, biocompatible artificial heart using advanced tissue engineering and soft robotics to improve the treatment of heart failure patients.
01
Develop a Biocompatible Artificial Heart:
Develop a Biocompatible Artificial Heart: Create a soft, biocompatible artificial heart using advanced tissue engineering and soft robotics to improve the treatment of heart failure patients.
02
Improve Life Expectancy and Quality of Life:
Enhance the survival rates and overall quality of life for heart failure patients who currently have limited treatment options.
02
Improve Life Expectancy and Quality of Life:
Enhance the survival rates and overall quality of life for heart failure patients who currently have limited treatment options.
02
Improve Life Expectancy and Quality of Life:
Enhance the survival rates and overall quality of life for heart failure patients who currently have limited treatment options.
02
Improve Life Expectancy and Quality of Life:
Enhance the survival rates and overall quality of life for heart failure patients who currently have limited treatment options.
03
Reduce Dependence on Donor Hearts:
Provide an off-the-shelf alternative to heart transplants, reducing the reliance on scarce donor hearts and addressing long waiting lists.
03
Reduce Dependence on Donor Hearts:
Provide an off-the-shelf alternative to heart transplants, reducing the reliance on scarce donor hearts and addressing long waiting lists.
03
Reduce Dependence on Donor Hearts:
Provide an off-the-shelf alternative to heart transplants, reducing the reliance on scarce donor hearts and addressing long waiting lists.
03
Reduce Dependence on Donor Hearts:
Provide an off-the-shelf alternative to heart transplants, reducing the reliance on scarce donor hearts and addressing long waiting lists.
04
Advance Medical and Scientific Knowledge:
Push forward the frontiers of regenerative medicine and soft robotics, contributing to new treatment strategies and scientific breakthroughs in cardiovascular health.
04
Advance Medical and Scientific Knowledge:
Push forward the frontiers of regenerative medicine and soft robotics, contributing to new treatment strategies and scientific breakthroughs in cardiovascular health.
04
Advance Medical and Scientific Knowledge:
Push forward the frontiers of regenerative medicine and soft robotics, contributing to new treatment strategies and scientific breakthroughs in cardiovascular health.
04
Advance Medical and Scientific Knowledge:
Push forward the frontiers of regenerative medicine and soft robotics, contributing to new treatment strategies and scientific breakthroughs in cardiovascular health.
01
Formulate project goals and objectives.
01
Formulate project goals and objectives.
01
Formulate project goals and objectives.
01
Formulate project goals and objectives.
02
Assemble a multidisciplinary research team.
02
Assemble a multidisciplinary research team.
02
Assemble a multidisciplinary research team.
02
Assemble a multidisciplinary research team.
03
Develop initial heart design prototype.
03
Develop initial heart design prototype.
03
Develop initial heart design prototype.
03
Develop initial heart design prototype.
Done
To do
04
Conduct in vitro performance testing.
04
Conduct in vitro performance testing.
04
Conduct in vitro performance testing.
04
Conduct in vitro performance testing.
05
Optimize materials for biocompatibility.
05
Optimize materials for biocompatibility.
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Optimize materials for biocompatibility.
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Optimize materials for biocompatibility.
06
Integrate soft robotics technology.
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Integrate soft robotics technology.
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Integrate soft robotics technology.
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Integrate soft robotics technology.
07
Create and test tissue-engineered linings.
07
Create and test tissue-engineered linings.
07
Create and test tissue-engineered linings.
07
Create and test tissue-engineered linings.
08
Validate prototype in animal models.
08
Validate prototype in animal models.
08
Validate prototype in animal models.
08
Validate prototype in animal models.
09
Refine design based on test results.
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Refine design based on test results.
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Refine design based on test results.
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Refine design based on test results.
10
Seek regulatory and ethical approvals.
10
Seek regulatory and ethical approvals.
10
Seek regulatory and ethical approvals.
10
Seek regulatory and ethical approvals.
11
Prepare for clinical trials.
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Prepare for clinical trials.
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Prepare for clinical trials.
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Prepare for clinical trials.
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Launch initial human trials.
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Launch initial human trials.
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Launch initial human trials.
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Launch initial human trials.
13
Collect and analyze clinical data.
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Collect and analyze clinical data.
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Collect and analyze clinical data.
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Collect and analyze clinical data.
14
Scale production for broader use.
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Scale production for broader use.
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Scale production for broader use.
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Scale production for broader use.
Facts and figures
The Holland Hybrid Heart project, with 15 Dutch institutions, develops a biocompatible artificial heart using soft robotics and tissue engineering. It addresses heart failure in 23 million globally and 1,400 Dutch patients annually, improving life expectancy and quality.
15
Did you know
The number of organizations that are a part of the Holland Hybrid Heart consortium.
15
Did you know
The number of organizations that are a part of the Holland Hybrid Heart consortium.
1400
Did you know
The number of advanced heart failure patients in the Netherlands who do not receive optimal treatment each year.
1400
Did you know
The number of advanced heart failure patients in the Netherlands who do not receive optimal treatment each year.
7 Years
Did you know
Holland Hybrid Heart project will last 7 years. In the end we hope to place a hybrid heart in a living animal.
7 Years
Did you know
Holland Hybrid Heart project will last 7 years. In the end we hope to place a hybrid heart in a living animal.
The Holland Hybrid Heart project, involving numerous scientists, offers heart failure patients improved life expectancy and quality of life, reduces wait times for donor hearts, suits more patients, and provides an innovative treatment option overcoming existing limitations.
Partners
Partners
Partners
Partners
Holland Hybrid Heart
seeks to create a biocompatible artificial heart using soft robotics and tissue engineering. This innovative heart aims to improve life expectancy and quality of life for heart failure patients while reducing reliance on scarce donor organs.
Holland Hybrid Heart
seeks to create a biocompatible artificial heart using soft robotics and tissue engineering. This innovative heart aims to improve life expectancy and quality of life for heart failure patients while reducing reliance on scarce donor organs.
Holland Hybrid Heart
seeks to create a biocompatible artificial heart using soft robotics and tissue engineering. This innovative heart aims to improve life expectancy and quality of life for heart failure patients while reducing reliance on scarce donor organs.
Holland Hybrid Heart
seeks to create a biocompatible artificial heart using soft robotics and tissue engineering. This innovative heart aims to improve life expectancy and quality of life for heart failure patients while reducing reliance on scarce donor organs.